Cancer
What Did the Research Discover? This study examined whether adding pembrolizumab (Keytruda), an immune checkpoint inhibitor, to standard chemotherapy before surgery could improve outcomes for patients with early-stage triple-negative breast cancer (TNBC). In this large phase 3 trial, 1,174 patients with stage II or III TNBC were randomly assigned
Bronchitis
What did the research discover? Researchers studied how activating a specific protein called Nrf2 could help the immune cells in the lungs, called alveolar macrophages, fight bacterial infections in chronic obstructive pulmonary disease (COPD). COPD makes it harder for these immune cells to remove harmful bacteria, leading to frequent lung
Cancer
What Are Current Prostate Cancer Treatments? Treating advanced prostate cancer often involves lowering the levels of male hormones (called androgens) in the body. This is because prostate cancer cells usually need these hormones to grow. One common treatment is called androgen deprivation therapy (ADT), which uses special medicines to stop
Arthritis
What did the research discover? Researchers explored quantitative imaging techniques that assess the biochemical composition of articular cartilage, offering early detection of osteoarthritis (OA) and new pathways for disease-modifying treatments. Traditional imaging methods like X-rays and standard MRIs fail to detect early-stage OA, while newer imaging techniques can measure cartilage
Cancer
What Did the Research Discover? Researchers conducted a phase 3 clinical trial to evaluate whether adding nivolumab, an immune therapy, to the standard chemotherapy drugs gemcitabine and cisplatin would improve survival for patients with advanced urothelial carcinoma (a type of bladder cancer). The study included 608 patients with unresectable or
Arthritis
What did the research discover? Researchers created a detailed map of the cells in the synovial tissue of people with rheumatoid arthritis (RA) by studying over 314,000 cells from 79 donors. They found six different types of cell patterns, called cell-type abundance phenotypes (CTAPs), which show various immune cell
Videos
Postpartum depression affects many new mothers, but there’s new hope. The FDA has approved a medication called Zurzuveet designed to help treat postpartum depression by rebalancing brain chemicals that regulate mood. In this video, we explain what postpartum depression is, how Zurzuveet works, and w
Health and Medical Research News
What did the research discover? This study explored how amyloid beta (Aβ), a protein linked to Alzheimer’s disease (AD), accelerates the process of protein insolubility that naturally occurs with aging. Protein insolubility happens when proteins clump together and lose their normal function, a hallmark of neurodegenerative diseases like Alzheimer’
Health and Medical Research News
What Did the Research Discover? Low back pain is a common condition that affects millions of people worldwide. Many people take pain relievers to manage their symptoms, but this study found that most medications offer little to no benefit. The research reviewed multiple studies on non-specific low back pain, which
Health and Medical Research News
What Did the Research Discover? Gastric and gastroesophageal junction (G/GEJ) cancers are among the deadliest cancers, and while immunotherapy has become a standard treatment for advanced cases, its role in earlier-stage disease is not well understood. The PANDA trial investigated whether neoadjuvant (before surgery) immunotherapy combined with chemotherapy could
FDA
<div class="inset-column"> <dl class="lcds-description-list--grid"> <dt class="cell-1_1">For Immediate Release:</dt> <dd class="cell-2_1"><time datetime="2025-02-28T05:00:00Z">February 28, 2025</time&
Health and Medical Research News
What Did the Research Discover? Zonisamide is an anti-seizure medication that has been used since 1989 to treat epilepsy. It is approved for different types of seizures in various countries, including the U.S., Europe, Japan, and Korea. It can be taken alone or alongside other seizure medications. Studies show